How To Bet This Week in College Hoops: Arizona-Houston, Michigan-Duke, More

The college basketball season has just a few weeks left, and NCAA Tournament positioning matters now more than ever. With that, let’s take a look at the odds for the biggest games on the schedule this week (at DraftKings Sportsbook as of Feb. 21), as well as what to know about each matchup. And check back throughout the week, as the games draw nearer and the odds update. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. MONDAY, FEB. 16 No. 2 Houston 67, No. 6 Iowa State 70 Spread: Iowa State -2.5 (ISU covers)O/U: 134.5 (Over hits) TUESDAY, FEB. 17 No. 1 Michigan 91, No. 7 Purdue 80 Spread: Michigan -2.5 (Michigan covers)O/U: 156.5 (Over hits) WEDNESDAY, FEB. 18 No. 20 Arkansas 115, No. 25 Alabama 117 Spread: Alabama -5.5 (Arkansas covers)O/U: 183.5 (Over hits) No. 23 BYU 68, No. 4 Arizona 75 Spread: Arizona -12.5 (BYU covers)O/U: 164.5 (Under hits) SATURDAY, FEB. 21 No. 1 Michigan vs. No. 3 Duke Spread: Michigan -2.5Moneyline: Michigan -148, Duke +124O/U: 150.5 What to know: Duke is 2-2 ATS in neutral site games this year, and 4-6 ATS against ranked opponents. The Wolverines are 3-1 ATS in neutral site games and 4-1 ATS against ranked opponents. Michigan has clearly established itself as the best team in college hoops, at 6-0 against ranked squads. One note: UM games have gone Under in 15 of 26 games this season, while Duke games have gone Under 18 of 26 times, including eight of the last 10. No. 4 Arizona @ No. 2 Houston Spread: Houston -6.5Moneyline: Houston -265, Arizona +215O/U: 141.5 What to know: Arizona is 6-1 on the road this season and 7-2 against ranked teams. However, at home, the Cougars are 13-0 overall and 8-5 ATS. So something will have to give. The 6.5-point spread is the most points by which Arizona has been an underdog all season, as the Wildcats had been favorites in 20 of their last 21 games. They were 3.5-point ‘dogs against Florida to open the season (won by six), 4.5-point ’dogs at UConn on Nov. 19 (won by four), and 1-point underdogs at BYU on Jan. 26 and won by three. No. 6 Iowa State @ No. 23 BYU Spread: Iowa State -2.5Moneyline: Iowa State -162, BYU +136O/U: 154.5 What to know: All three of the Cyclones’ losses have come on the road this season, and they are 4-3 ATS away from home. They will have a chance to reverse that trend when they take on a BYU team that is 3-4 ATS against ranked opponents and 1-6 straight-up against ranked foes. Iowa State has covered in six of its last eight games.